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Hyaluronidase 1500IU

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Hyaluronidase (Ovine)

Strength: 1500IU per vial.
Box contains: 5 vials
Use: Dissolving HA filler.

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Hyaluronidase is made of enzymes that catalyse the degradation of hyaluronic acid (HA). Hyaluronidase's active ingredient reverses hyaluronic acid based dermal filler procedures by breaking down its content and dissolving the filler completely.

Perform a hyaluronidase Ovine allergy test:

Perform a patch test on: Clean the skin and mark out the test area. Subcutaneously inject a tiny amount of Hyaluronidase and wait 10-20 minutes to monitor any adverse responses or allergies, even though they are uncommon. Despite the fact that it is not a strictly mandatory step, a patch test is usually recommended, especially if the treatment is not an emergency. Erythema is normal after injection of hyaluronidase and it will subside right after the treatment.

Treatment with hyaluronidase is contraindicated if there are symptoms of urticaria or an allergic reaction.

  • Content: Hyaluronidase Ovine (purified) 1500 I.U.Mannitol
  • Manufacturer: Laboratoires Elviderm, France.
  • Form: Freeze-dried white powder in a glass vial.
  • Administration: Subcutaneous and intramuscular injection. (no intravenous injections).

To dissolve hyaluronic acid filler:

For each 1mL of hyaluronic acid gel, use 100-150 Units of hyaluronidase.

Hyaluronidase Reconstitution:

  1. Use normal saline NaCl 0.9%.
  2. Use 10mL of saline to reconstitute a 1500IU hyaluronidase vial.

What's in the box: 

The box contains 5 vials of hyaluronidase, 1500IU/vial.

Please note that Saline is not provided. Order Saline solution 0.9%

Click the following link for an overview video of Hyaluronidase

For in-depth information on Hyaluronidase 1500iu, read our article "Hyaluronidase the Ultimate Guide".

Frequently asked Questions:

Can a vascular occlusion occur from a Hyaluronidase injection?

Not at all. Hyaluronidase doesn't cause occlusions of any kind. On the contrary it is used to treat and unblock vascular occlusions, when we say occlusions we mean the ones caused by HA filler or related products.

Can Hyaluronidase ruin my lips?

No it won't. Hyaluronidase is totally safe to be used in the lips and it will only dissolve the Ha deposits.

Will facial fat dissolve by using hyaluronidase?

It is not possible to dissolve fat with hyaluronidase. Therefore, dissolving hyaluronic acid fillers in a fatty region will not affect the fat tissue. As a side note, skin texture will not be affected by hyaluronidase either.

Can permanent damage occur from using hyaluronidase?

Hyaluronidase does not cause permanent damage if used safely (under supervision of medical professionals) and in moderate dosage. Bruising, redness or skin irritation at the injection site is only temporary and will resolve in no time.

Can I use anesthetic products (for numbing) with Hyaluronidase?

Topical (Emla or similar) and local anesthetic can be safely used prior to administering hyaluronidase.

Can hyaluronidase migration occur?

Migration of hyaluronidase is uncommon.

Hyaluronidase: capable of causing swelling?

Bruising and swelling occur after any injectable treatment however that's only temporary and subsides shortly after treatment.

How soon does hyaluronidase start to work?

The filler starts dissolving immediately after injection. Effects are noticeable within 3 hours after the injection. And the full effect is seen in 24-48 hours after treatment.

Is all filler dissolvable with hyaluronidase?

Not all products are dissolved with Hyaluronidase. Hyaluronic acid fillers are the only type that can be dissolved by a Hyaluronidase injection. During this process the HA is converted from gel into fluid.

After Hyaluronidase, am I able to get dermal filler again?

After being dissolved by the hyaluronidase enzyme, a hyaluronic acid dermal filler (or other) can indeed be injected once again. It just depends on when. There needs to be a gap between dissolving and replenishing, depending on the situation this has to be evaluated by a professional assessment.

Is Botox reversible with Hyaluronidase 1500 IU?

No, hyaluronidase has no impact whatsoever on Botox nor does it reverse its effects. Only hyaluronic acid based products are dissolvable with hyaluronidase 1500 iu. Because HA is not present in botox, the enzyme hyaluronidase cannot impact it.

Will Hyaluronidase dissolve my natural hyaluronic acid?

If hyaluronidase is used correctly and safely it won't cause loss of natural hyaluronic acid. It also won't disintegrate or harm other healthy tissue.

How soon can I have filler after using hyaluronidase?

The grace period is typically 5 days, however it varies depending on each individual case. To be safe, it is highly advisable to wait 2 weeks after dissolving an HA dermal filler before receiving another one.

Where can I buy Hyaluronidase?

You can buy hyaluronidase from many different sources, such as local medical suppliers or online suppliers. You can also buy Hyaluronidase from by placing your order directly on our website or by calling us at (646)665-7222.

Do you sell Liporase hyaluronidase?

We do not sell Liporase hyaluronidase due to the lack of transparency in its manufacturing process. The manufacturer of Liporase does not disclose enough data about their manufacturing facility in Asia, nor do they disclose data about the raw materials used, the purification process, their certification and compliance. Any healthcare professional should be concerned about that, and that's why we will not stock Liporase.

Below are some products that can be dissolved by Hyaluronidase 1500 IU injection:
The list includes a wider range of products and is not limited to the ones below, 

Restylane Fillers such as:

7 Reviews

Superior to Hylenex. And has more vials per box.

Effective and yields good results :)

good stuff! And fast Fedex shipping! Thx ❤️

As good as Hyalase

Good product, and priced well.

Great product! :)

5 Stars
We had good results with this product

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